大侦探福尔摩斯（小罗伯特·唐尼 Robert Downer Jr. 饰）即使在置人于死地之时也异常的逻辑清晰，然而办案时有条不紊的他在私底下的生活中简直就是个“怪胎”，至少在他的助手华生医生（裘德·洛 Jude Law饰）眼中他是这样一个人。他们亲手绳之以法的“黑暗巫师”布莱克大人（马克·斯特朗 Mark Strong 饰）在临死前说死亡即是开始，随后艾琳·艾德勒（瑞秋·麦克亚当斯 Rachel McAdams 饰）出现在他的身边要他帮忙找个失踪的人，而她身边有个影子般可怕人物。坊间传说黑暗巫师已经复活，他的墓地遭到破坏，而躺在棺材里的人另有其人。又到了大侦探福尔摩斯出马的时候了，然而调查过程从一开始就险象环生，助手华生医生在调查中更是险些丧命，福尔摩斯也陷入连串的迷团之中。
电影描绘了电视剧版发生的故事之后，两人再次相遇，再一次作为搭档开始接受工作委托后的最初的案件。福尔摩斯研究家和福尔摩斯粉丝称为“夏洛克·福尔摩斯”系列史上最高杰作的长篇杰作《巴斯卡维尔的猎犬》的故事作为原案。日本屈指可数的资本家委托若宫为他搜寻女儿绑架未遂事件的犯人。但在那之后，资本家留下庞大的遗产，离奇地死去。为了探听资本家的死和绑架事件的真相，狮子雄和若宫降落在濑户内海的某个岛上。等待他们的是，一个一个都很难对付的华丽一族和奇怪的关系者们。和周围阻断的这个岛上，人们窃窃私语着传说中会袭击人的可怕魔犬的所作所为。连锁反应一样接二连三地发生了案件。复杂的人际关系和交错的现在与过去。这是不能打开的“潘多拉之盒”吗？同时若宫也面临着穷途末路的危机。这时候，狮子雄的决断是？这之后，两人终于抵达的可怕真相又是？
Loosely based on the "Sherlock Holmes" series by Sir Arthur Conan Doyle, Sherlock Hound turns all the classic characters into dogs. The canine Sherlock Holmes, his assistant Watson, and housemaid Mrs. Hudson work together to solve mysteries. The culprit is usually Professor Moriarty and his gang, who use all kinds of wacky contraptions to steal what they want.
Sherlock has a peculiar character flaw. She does not open her heart to strangers. She is Japanese, but was born in Britain. She now works as an investigation consultant for the police department. Wato Tachibana is an excellent surgeon and is guided by the principal of justice. Sherlock and Wato Tachibana get to know each other through a case and begin to rely on each other.
This mystery thriller throws a Russian spin on one of the world’s most famous characters, the series follows the esteemed detective from London to stunning St Petersburg, on the trail of a suspected serial murderer. Sherlock Holmes (Maxim Matveyev) is on the hunt for Jack the Ripper. The infamous killer left a bloody trail in London and fled to the Russian Empire, with Sherlock on his tail. With new characters, Dr Kartsev and Sophia supporting Sherlock, and a new nemesis in Znamensky, this is an exciting, glossy action series.
