Follow the infamous ninja bandit named Ishikawa Goemon (Yosuke Eguchi) in an epic story. One night while looting treasure from Nanban (Southern Barbarians), Goemon finds a mysterious box hidden inside a secret grave. A forgotten relic from the past containing untold powers.
The story follows the social intercourse between a cameraman, Masaya, with a visual impairment, and Misako who disconnects from the world.
One year has passed after the great battle against the Orochi (gigantic snake). Tenka Kumo had been paralyzed from the final battle and he took part of the government’s human experiment before the battle. Tenka withdrew himself from society but his younger brothers Soramaru and Chutaro find out the secret past about their older brother.
Fuma ninja clan is a secret ninja tribe that is waiting for the "Orochi" (gigantic snake) to resurrect for generations. Shirasu and his twin brother Ichiu grew up in this viscous environment and this tells how they become the leaders of the clan.
A record company office worker named Kanna discovers a punk rock band called Shonen Meriken Sakku 'Brass Knuckle Boys' through the internet and subsequently decides to represent them on behalf of her company. What Kanna did not know was that the Brass Knuckle Boys consists of all middle aged men.
The three brothers discover that the human experiment banned after destroying the "Orochi", is still going on to secretly revive the evil snake. They also find out that some ex-members of the Yamainu (the Japanese military unit formed to kill the snake) are behind this conspiracy. The brothers fight together again in a battle against the military.
Home-design sales representative Tomohiro lives with his wife and their son. As his job involves houses, it is his motto to take great care of the family who live in the house. However, he has been working so hard that he has forgotten to cherish his own family. When he looks after a client who wants to leave her father-in-law in a nursing home, it reminds him of his grandmother whom he loved so much. Father's death, grandmother's struggle with disease, and home care - those were grueling times, but the memories have become invaluable for Tomohiro. He realizes his family is the most precious thing of all. On a day off, he and his family decide to visit his mother who lives alone in their old hometown.
