The Newton family live in their comfortable home, but there seems to something missing. This "hole" is filled by a small puppy, who walks into their home and their lives. Beethoven, as he is named, grows into a giant of a dog... a St Bernard. Doctor Varnick, the local vet has a secret and horrible sideline, which requires lots of dogs for experiments. Beethoven is on the bad doctor's list.
A research scientist becomes the world's first pregnant man in order to test a drug he and a colleague have designed for expectant women. To carry out the trial, he has an embryo implant, believing that he will only carry the baby for three months – hardly expecting to face the prospect of giving birth.
In the South Pacific island of Makatea, career-driven magazine editor Robin Monroe is on a week-long vacation getaway with her boyfriend, Frank Martin. An emergency work assignment in neighboring Tahiti requires Robin to hire the cantankerous pilot Quinn Harris who had flown them to Makatea on a small transport plane. While flying, a powerful storm forces Quinn to make an emergency landing on a nearby deserted island. The dissimilar pair avoid each other at first, until they're forced to team up to escape from the island -- and some pirates who want their heads.
Beethoven is back -- and this time, he has a whole brood with him now that he's met his canine match, Missy, and fathered a family. The only problem is that Missy's owner, Regina, wants to sell the puppies and tear the clan apart. It's up to Beethoven and the Newton kids to save the day and keep everyone together.
A tough police sergeant's mother comes to visit him, and promptly starts trying to fix up his life, much to his embarrassment. For his birthday she buys him a machine gun out of the back of a van, and begins to further interfere with his job and love life, eventually helping him with a case he's on.
A sweet-natured Temp Agency operator and amateur Presidential look-alike is recruited by the Secret Service to become a temporary stand-in for the President of the United States.
A woman cons two old boyfriends into searching for her runaway son by convincing both that they are the boy's father.
District Attorney Tom Logan is set for higher office, at least until he becomes involved with defence lawyer Laura Kelly and her unpredictable client Chelsea Deardon. It seems the least of Chelsea's crimes is the theft of a very valuable painting, but as the women persuade Logan to investigate further and to cut some official corners, a much more sinister scenario starts to emerge.
David Letterman vies with Jay Leno and his manager to succeed Johnny Carson, retiring from "The Tonight Show."
Seth Warner has reached the end of his rope. Ever since his wife died two years earlier, his world has been in turmoil. He is despondent, his career has fallen apart, even his house has been destroyed. There seems to be nothing left for him to live for. Confused and angry after two years of suffering, he finally directs his wrath at God from the rooftop of his apartment building in New York City. In the midst of a wild thunderstorm he demands to know why he has been betrayed by the god he has believed in and honored his whole life. God's answer is to strike down Seth's dog in a bolt of lightning. Pushed beyond his limits, Seth decides to respond to his years of torment by breaking each of the biblical Ten Commandments.
At the beginning of a nightly Alcoholics Anonymous meeting, Jim seems particularly troubled. His sponsor encourages him to talk that night, the first time in seven months, so he does - and leaves the meeting right after. As Jim wanders the night, searching for some solace in his old stomping grounds, bars and parks where he bought drugs, the meeting goes on, and we hear the stories of survivors and addicts - some, like Louis, who claim to have wandered in looking for choir practice, who don't call themselves alcoholic, and others, like Joseph, whose drinking almost caused the death of his child - as they talk about their lives at the meeting
